Vitamin D for Inflammatory Bowel Disease

Vitamin D for Inflammatory Bowel Disease

“Vitamin D for Inflammatory Bowel Disease” Inflammatory bowel disease is a chronic
inflammatory condition of the intestine that includes Crohn’s disease
and ulcerative colitis. If you compare identical twins, even
though they have the same genes, most of the time if one twin
has it, the other does not. So there must be some important
nongenetic trigger factors. What might they be?
Well, studies like these offered a clue. Why do those living in the southern
United States have lower IBD rates than those living in the north? Maybe it’s because those living
in the south get more sun, which means more vitamin D,
which may mean less inflammation. So do those with Crohn’s and
ulcerative colitis with low vitamin D levels have worse disease?
Apparently so. Increased risk of surgery
and hospitalization. And those that normalized
their vitamin D levels appeared to reduce
their risk of relapse. But instead of better vitamin D
leading to better Crohn’s, maybe the better Crohn’s
led to better D. They felt so good they
went outside more. You can’t tell if it’s cause and effect
unless you put it to the test. The first pilot study tried
a thousand units of vitamin D a day and saw no change in the
Crohn’s disease activity index, though at 6 weeks there may
have been a slight increase in inflammatory bowel disease
quality of life scores. But even that disappeared by year’s end.
Pretty disappointing results. Maybe they didn’t use enough.
How about 1200 a day? The relapse rate appeared
to be cut in half, though there were too few people in the
study to reach statistical significance. How about 2,000 international
units of vitamin D a day? Gut leakiness, so called
intestinal permeability, continued to worsen in the placebo
group, but appeared to stabilize in the Vitamin D group, though only
those who reached blood levels over 75 nanomoles per liter appeared to
have a significant drop in inflammation. And indeed, if you start Crohn’s patients
on a thousand and then ramp it up until they reach a target blood level,
you can get a significant boost in quality of life, accompanying a
significant drop in disease activity. Disease scores under 150
are considered remission, so the majority of patients
achieved remission, with improvements in disease
activity in all but one patient. This suggests that Crohn’s
patients may want to take 5,000 international units
of vitamin D a day. But that’s nearly 10 times the RDA.
Why so much? Because that’s what it may take
to get normal vitamin D levels, as in normal-for-our-species levels,
the kind of levels one might get running around half naked in Africa,
as we did for millions of years.

34 thoughts on “Vitamin D for Inflammatory Bowel Disease”

  1. Been taking 3000 IU of vitamin D for a month, haven't noticed much of a difference this year in winter, but last year just by taking 2000 IU for 2-3 months in winter I definitely noticed that I felt better. I wonder why that might be? I will still continue taking it because where I live only in summer I can get out during the day without a jacket on.

  2. If I don't want to take supplements, the only way I could archieve my daily vitamin d intake is by just start running around naked all day long even in winter I suppose? 😀 If everyone did it, it'd be consider normal I think 😀

  3. Does anyone have suggestions on mail in test kits? I found a few on amazon for appox $50, 68, and more. Just wondering if these are good enough.

  4. And when you take high dosage of d3 you have to take 1/10 the dosage about of K2 which is found in meats or fermented bacteria like yogurt. You also need calcium and magnesium which helps in absorption. Also you need cholesterol to absorb with or without sun.
    If you get if from the sun it has to be at peak hours and you should not get a burn from UVA and you should not use soap for 2 days to absorb it 100%.
    If you disagree ok good luck.
    Also other factors are not mentioned like how people walk more, get more fresh air, when its warmer outside how people sweat more to release more toxins, how if they swim more it helps etc and many other factors.

  5. Where are good places to buy Vit d supplements. Is my local shop Holland and Barrett a good place its in the UK where i live

  6. Would this work if I took the equivalent vitamin D but as 3 doses a month? I have a capsule that contains 50,000IU I usually take once a month, I could increase to 3 times to get the equivalent of taking 1 5000IU capsule daily?

  7. I haven't had an ulcerative colitis flare up since 2012 when I finally gave up dairy. A lot of colitis and crohns patients are having allergic reactions to food, and it's usually the protein in said food that's causing the problem. Going on a low protein plant based diet often gets rid of any offenders and people start to feel better.

  8. I take 5000 mg a a day, but stop because I started taking seniors multi vitamins but it has less. I am not sure if I can continue my D as I was doing. I prefer to leave the multi vitamins, better. I live in Florida but i don't like to get suntanned, I get spots, no like of warm weather, so I don't go out unless in my son's car to do my errands. So I take the pills. Can I have an hyper vitamin D side effect by taking them everyday forever?

  9. Your "put it to the test" cameo just made me realize you need to make a rap/song/music video and I think it would be a huge hit!

  10. Dear Dr Greger. Please may I ask where I can buy a very concise text on what you recommend eating, drinking and supplementing with. I know you have a book but I'm happy to pay more for somthing scaled down,as I am already convinced of your science and stance on eating in general. I'm looking basically for a list with the most important items at the top, if you will. Many thanks fan from the UK.

  11. Now if all doctors would only use the scientific method instead of guessing and doing sh!t for people. They have to learn to STOP guessing and starting diagnosing properly. Most doctors don't even test D levels, even in crohn's patients. Its utter retardism to the max.

  12. How do you balance this line of thinking with the video on D causing more fractures? Supplement 1000 per day, 5000 per day, or none, and depend on our Whole food plant based eating. From a 50 year old vegan with IBS

  13. I have intestinal issues when I eat oatmeal. I won't get graphic but you get the idea. Is this normal for oatmeal?

  14. Take the minimum amount possible in the form of supplement, use supplements as back ups 'just in case' and focus on getting your d from the sun.

  15. I've been having UC flare-ups for months. I was trying to find the food that was doing it to me without any relief. The only thing that worked, but I hated doing was to smoke a couple of packs of coffin nails and the flare-ups went away.

    Then I got shin splints when the dogs dragged me down a hill too quickly.

    I then learned that low vitamin d made me more susceptible to shin splints.

    I started taking d3 several times a day and the shin splints went away in record time.

    This was at the start of another UC flare-up, but low and behold, the flare-up went away without having to resort to smoking.

    I can't believe it was that simple a "cure". As a Canadian, I should have known better.

    I hope this is a long term result. I never want to need to smoke again to stop a flare-up. Nor do I want to suffer from shin splints.

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